CHAMP – Child Health And Microbiome Development Study, Pakistan
The CHAMP study aimed to longitudinally assess oral and gut microbiome development and associated factors during early childhood in populations residing in m…
View projectResearch theme
The human mouth harbours one of the body's most diverse microbial ecosystems, playing a vital role in both oral and systemic health. Our research explores how oral microbial communities develop, function, and interact with the host across health and disease. We are particularly interested in oral microbiome development in children at risk of malnutrition and its implications for oral health, growth, and development. We also investigate how smokeless tobacco use, particularly naswar, alters the oral microbiome and contributes to disease risk, including oral cancer.
Research theme
The gut microbiome plays a fundamental role in nutrition, metabolism, immune function, and healthy development. Our research focuses on how gut microbial communities develop during early life, particularly among children at risk of malnutrition. We investigate how alterations in the gut microbiome influence growth, development, and health outcomes, with the goal of identifying microbiome-based strategies to support child health and reduce the burden of malnutrition.
Research theme
Nutrition and the microbiome are closely interconnected, with diet shaping microbial communities and, in turn, the microbiome influencing nutrient metabolism, growth, and health. Our research explores how dietary intake and nutrition influences microbiome development and function, and how microbiome alterations may contribute to impaired growth, development, and health outcomes. Through this work, we aim to identify pathways and interventions that can support healthy growth and improve nutritional health.
Research theme
Our public health research focuses on understanding the factors that shape health and well-being across the life course, with particular emphasis on oral health, growth, and development. We investigate how dietary intake, nutritional status, and other social and environmental determinants influence health outcomes, especially among vulnerable populations. Through population-based research, we aim to generate evidence that informs effective interventions, policies, and programs to improve health and reduce health disparities.
No projects or publications yet under this theme.
Browse all
The CHAMP study aimed to longitudinally assess oral and gut microbiome development and associated factors during early childhood in populations residing in m…
View projectEarly childhood malnutrition, a leading cause of morbidity and mortality, is widespread in Pakistan. While gut microbiome dysbiosis and intestinal barrier dy…
Funder: Nestlé Foundation, Switzerland
View projectModern lifestyles, changing diets, urbanization, and increased antibiotic exposure are rapidly transforming the human microbiome. However, the composition an…
View projectSmokeless tobacco (Naswar) use is an issue of public health concern in Khyber Pakhtunkhwa (KP) province of Pakistan. Epidemiological evidence suggests a stro…
View projectIn this project, we investigated the gut microbiome of adolescent Afghan refugees to understand how nutrition and health shape microbial communities in vulne…
View projectThe first five years of life are a critical period for the development of the oral and gut microbiomes, which interact with nutrition, immunity, growth, and …
Funder: Swiss National Science Foundation, Switzerland
View project